Frontline Plus for dogs is a topical medication that works against flea and tick infestations. Its active ingredients, S-methoprene and fipronil, act not only to kill all existing ticks and fleas, but also act on flea eggs and larvae to ensure that they do not mature into adults. This drug is known to be 100% effective within the first 48 hours of application. Apart from this, Frontline Plus is also preferred by many due to its long lasting effect. Once applied, this medication can be effective for a whole month, even if you bathe your dog or take him swimming. This is because fipronil accumulates in the animal’s sebaceous glands, from where it is constantly released onto the skin and coat.

Frontline Plus for Dogs is a safe medication to use and can be used in puppies and kittens as early as two days after birth. Although the side effects of this drug are not common, they sometimes occur and are mainly related to the alcohol used as a solvent.

Frontline Plus for dogs: side effects to watch out for

If side effects occur after the use of Frontline Plus for dogs, they would generally be related to effects on the skin. There are also side effects that have sometimes been considered neurological or mental in nature.

Skin-related side effects

An immediate reaction that your dog might have after applying the medication is skin irritation. Itching and hair loss at the application site have also been reported in some dogs. Skin irritation usually manifests itself as redness or discoloration of the skin and itching. Most of the time, the side effect is temporary and subsides within a few days. However, if the irritation does not subside or appears to be more severe than before, you should immediately consult your veterinarian.

When skin irritation occurs, your dog will try to scratch the area. This will aggravate the condition. Therefore, keep an eye on your pet and avoid scratching because scratching will cause the medicine to spread to its paws and other areas of its body, which it can lick. Scratching could also cause the area to bleed, which in turn would cause the drug to enter the bloodstream.

Neurological side effects

Some of the neurological side effects could include:

• Increased drooling
• Excess sensitivity to noise, light or touch.
• Keep quiet and look depressed
• Aggression and anxiety
• High heart rate
• Respiratory or respiratory effects
• Panting and vomiting have also been observed in some dogs, although they disappear quickly.

If you notice any of these symptoms persist in your pet, see your vet immediately.

Frontline Plus for dogs: effects on humans and other species

Side effects in humans are rare. The most frequently reported effects are irritation of the skin, mouth and eyes. If this happens, immediately wash the affected area with plenty of clean water. The best way to avoid this effect is to apply Frontline Plus for dogs just before bedtime and let the medicine dry completely overnight before cuddling the dog. Do not allow your dog to sleep in your bed after applying the medication. Although severe reactions are extremely rare, humans can experience vomiting, agitation, and seizures. If such effects occur, you should immediately consult your doctor.

As for its effects on other species, the first thing to remember is not to apply Frontline Plus for dogs in cats. This medication is available specifically for cats. This medicine could be fatal to rabbits and aquatic species, so proper care must be taken to prevent these species from coming into contact with the medicine.